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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NBEAL2 All Species: 5.15
Human Site: S2458 Identified Species: 10.3
UniProt: Q6ZNJ1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZNJ1 NP_055990.1 2754 302517 S2458 S G P W V P G S G V S G Q A L
Chimpanzee Pan troglodytes XP_525997 2750 313008 L2453 N G S F A P G L E I T S K L F
Rhesus Macaque Macaca mulatta XP_001094456 2295 260424 L2007 H M D I V T C L A T D Y C G I
Dog Lupus familis XP_541900 2305 251162 A2017 D G S L R V T A L P R G K L L
Cat Felis silvestris
Mouse Mus musculus Q6ZQA0 2742 301906 S2446 S G P W V S D S G V S A Q A L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508701 2269 259447 G1981 L R S P N I Y G T R S P Q E L
Chicken Gallus gallus XP_421964 2298 259902 L2010 G L E I T S K L F A V S H D A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W4E2 3584 396477 P3111 L P P W A K S P E E F V R I N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19317 2507 281187 A2218 A R R H L G D A F D Q R L T V
Sea Urchin Strong. purpuratus XP_785921 3355 375569 H3057 G P F A P G M H V T A K L F V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_182078 2946 321916 S2624 Q A Q A F A S S G I R S S S V
Baker's Yeast Sacchar. cerevisiae P25356 2167 250854 I1879 N R S V D Y V I H D P S Y F D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.1 40.2 74.6 N.A. 88 N.A. N.A. 39.7 40.6 N.A. N.A. N.A. 20.7 N.A. 21.1 33.4
Protein Similarity: 100 65.6 56.3 77.1 N.A. 92 N.A. N.A. 53.8 55.7 N.A. N.A. N.A. 36.1 N.A. 37.4 48.8
P-Site Identity: 100 20 6.6 20 N.A. 80 N.A. N.A. 20 0 N.A. N.A. N.A. 13.3 N.A. 0 0
P-Site Similarity: 100 53.3 13.3 33.3 N.A. 80 N.A. N.A. 20 0 N.A. N.A. N.A. 20 N.A. 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 20.6 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. 36.5 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 17 17 9 0 17 9 9 9 9 0 17 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % C
% Asp: 9 0 9 0 9 0 17 0 0 17 9 0 0 9 9 % D
% Glu: 0 0 9 0 0 0 0 0 17 9 0 0 0 9 0 % E
% Phe: 0 0 9 9 9 0 0 0 17 0 9 0 0 17 9 % F
% Gly: 17 34 0 0 0 17 17 9 25 0 0 17 0 9 0 % G
% His: 9 0 0 9 0 0 0 9 9 0 0 0 9 0 0 % H
% Ile: 0 0 0 17 0 9 0 9 0 17 0 0 0 9 9 % I
% Lys: 0 0 0 0 0 9 9 0 0 0 0 9 17 0 0 % K
% Leu: 17 9 0 9 9 0 0 25 9 0 0 0 17 17 34 % L
% Met: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 17 25 9 9 17 0 9 0 9 9 9 0 0 0 % P
% Gln: 9 0 9 0 0 0 0 0 0 0 9 0 25 0 0 % Q
% Arg: 0 25 9 0 9 0 0 0 0 9 17 9 9 0 0 % R
% Ser: 17 0 34 0 0 17 17 25 0 0 25 34 9 9 0 % S
% Thr: 0 0 0 0 9 9 9 0 9 17 9 0 0 9 0 % T
% Val: 0 0 0 9 25 9 9 0 9 17 9 9 0 0 25 % V
% Trp: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 9 0 0 0 0 9 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _